The DS3R was designed as an inexpensive essentials board and it exceeds its quota. While we cannot recommend the board for Multi-GPU purposes that doesn't mean you can't use a good single card or a GX2/X2 or the second slot for another Nvidia card for PhysX. Like any P45 if you can tweak the nuts off it the performance is exceptionally good - and the Gigabyte has plenty of options that work (!!) to do this