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Microsoft has released a new preview build of Windows 10, Build 14251 for PCs to members of the Windows Insider Fast ring



From Windows Central:
Microsoft did note that the following bugs have been fixed:

We fixed the issue where some PC games would crash switching from windowed mode to full screen, upon game resolution change, or upon launch due to a bug in Windows graphics stack. So play your games! If you run into any issues – please let us know by reporting in the Feedback app and include the game title.
We fixed the issue where applications such as Narrator, Magnifier, and third-party assistive technologies may experience intermittent issues or crashes.
We fixed an issue where File Explorer would crash frequently when DPI settings were at 175%.

On the topic of the build number jump, Microsoft says:

"As part of our work getting the common codebase ready for the next release, we decided to complete that work and sync the build numbers between mobile and PC. Because the mobile codebase used higher build numbers than PC, we needed to jump ahead a bunch of build numbers to ensure updates to future builds will continue to work."
  Windows 10 PC preview build 14251 now available for the Insider Fast ring