As usual for many USB devices, you install the software, then you plug in the gadget. The main e40 driver software is called "ScanWise". It works with Windows 98 and 2000, and USB-equipped Macintoshes.

Agfa´s Windows software installer uses a cheery interface that looks nothing like anything Windows or Mac OS normally displays, and you get to see a funky animated "About ScanWise" presentation before you can actually start installing, whether you like it or not.